Christian Flotho

Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia

Charlotte M. Niemeyer, Michelle Kang, Danielle H. Shin et al. · Nature Genetics · 2010 · 373 citations

Life Sciences, Genetics, Molecular Genetics +15

Effect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia

Franco Locatelli, Gerhard Zugmaier, Carmelo Rizzari et al. · JAMA · 2021 · 325 citations · Full text

Medicine, Hematology, Pediatrics +17

The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells

Christian Flotho, Rainer Claus, Christiane Batz et al. · Leukemia · 2009 · 316 citations

Life Sciences, Molecular Biology, Oncology +17

Mutations in CBL occur frequently in juvenile myelomonocytic leukemia

Mignon L. Loh, Debbie S. Sakai, Christian Flotho et al. · Blood · 2009 · 288 citations · Full text

Medicine, Genetics, Molecular Genetics +10

RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML)

Christian Flotho, S Valcamonica, Sara Mach‐Pascual et al. · Leukemia · 1999 · 193 citations

Medicine, Genetics, Pediatrics +16