Christian Flotho

Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia

Charlotte M. Niemeyer, Michelle Kang, Danielle H. Shin et al. · Nature Genetics · 2010 · 365 citations · Full text

Hematological Malignancy, Chromatin, Developmental Biology +10

Effect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia

Franco Locatelli, Gerhard Zugmaier, Carmelo Rizzari et al. · JAMA · 2021 · 313 citations · Full text

The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells

Christian Flotho, Rainer Claus, Christiane Batz et al. · Leukemia · 2009 · 311 citations

Dna Methyltransferase Inhibitors, Chromatin, Hematological Malignancy +12

Mutations in CBL occur frequently in juvenile myelomonocytic leukemia

Mignon L. Loh, Debbie S. Sakai, Christian Flotho et al. · Blood · 2009 · 285 citations · Full text

RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML)

Christian Flotho, S Valcamonica, Sara Mach‐Pascual et al. · Leukemia · 1999 · 191 citations

Hematological Malignancy, Clonality Analysis, Pediatric Hematology +8