Concepedia

The cationic lipid, diC14 amidine, extends the adjuvant properties of aluminum salts through a TLR-4- and caspase-1-independent mechanism

Arnaud Wilmar, Caroline Lonez, Marjorie Vermeersch, Mathieu Andrianne, David Pérez‐Morga, Jean‐Marie Ruysschaert, Michel Vandenbranden, Oberdan Léo, Stéphane Temmerman

Vaccine · 2011 · 25 citations · 27 references

DOI

Concepts

References

27

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung, Franz Bauernfeind, Annett Halle et al. · Nature Immunology · 2008 · 3K citations · Full text

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Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

Stephanie C. Eisenbarth, Oscar R. Colegio, William O’Connor et al. · Nature · 2008 · 1.5K citations · Full text

, , +14

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

Mirjam Kool, Thomas Soullié, Menno van Nimwegen et al. · The Journal of Experimental Medicine · 2008 · 983 citations · Full text

, , +16

The Vaccine Adjuvant Monophosphoryl Lipid A as a TRIF-Biased Agonist of TLR4

Verónica Mata‐Haro, Caglar Cekic, Michael Martin et al. · Science · 2007 · 891 citations

, , +16

AS04, an Aluminum Salt- and TLR4 Agonist-Based Adjuvant System, Induces a Transient Localized Innate Immune Response Leading to Enhanced Adaptive Immunity

Arnaud M. Didierlaurent, Sandra Morel, Laurence Lockman et al. · The Journal of Immunology · 2009 · 742 citations · Full text

, , +17