Defect in normal developmental increase of the brain biogenic amine concentrations in the mecp2-null mouse

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Ruthie E. Amir, Ignatia B. Van den Veyver, Mimi Wan et al. · Nature Genetics · 1999 · 5K citations

Life Sciences, Genetics, Molecular Genetics +9

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

Jacky Guy, Brian Hendrich, Megan C. Holmes et al. · Nature Genetics · 2001 · 1.6K citations

Life Sciences, Genetics, Neuroscience +14

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

Richard Z. Chen, Schahram Akbarian, Matthew Tudor et al. · Nature Genetics · 2001 · 1.3K citations

Life Sciences, Neurobiology, Neuroscience +14

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

Wen Chen, Qiang Chang, Yingxi Lin et al. · Science · 2003 · 1.2K citations

Life Sciences, Molecular Biology, Neuroscience +17

Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome

Shin‐ichi Horike, Shutao Cai, Masaru Miyano et al. · Nature Genetics · 2004 · 576 citations

Life Sciences, Genetics, Molecular Genetics +16