Jacky Guy

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

Jacky Guy, Brian Hendrich, Megan C. Holmes et al. · Nature Genetics · 2001 · 1.6K citations

Knockout Mouse, Molecular Neuroscience, Mendelian Disorder +12

Reversal of Neurological Defects in a Mouse Model of Rett Syndrome

Jacky Guy, Jian Gan, Jim Selfridge et al. · Science · 2007 · 1.2K citations · Full text

Neurological Disorder, Rett Syndrome, Neurological Defects +17

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

John P. Thomson, Peter J. Skene, Jim Selfridge et al. · Nature · 2010 · 642 citations · Full text

Chromatin, Transcriptional Regulation, Systems Biology +9

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

Matthew J. Lyst, Robert Ekiert, Daniel H. Ebert et al. · Nature Neuroscience · 2013 · 397 citations · Full text

Signal Transduction, Mendelian Disorder, Rett Syndrome Mutations +7

Enhanced CpG Mutability and Tumorigenesis in MBD4-Deficient Mice

Catherine B. Millar, Jacky Guy, Owen J. Sansom et al. · Science · 2002 · 327 citations · Full text