Publication | Open Access

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

Signal TransductionSignaling PathwayCell RegulationMedicineReceptor Tyrosine KinaseMolecular BiologyProtein PhosphorylationConstitutive PhosphorylationCell BiologyCell SignalingTumor Biology