Frederick Y. Wu

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

Shizhen Emily Wang, Archana Narasanna, Marianela Pérez-Torres et al. · Cancer Cell · 2006 · 464 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +8

A novel viral mechanism for dysregulation of β-catenin in Kaposi's sarcoma–associated herpesvirus latency

Masahiro Fujimuro, Frederick Y. Wu, Colette Aprhys et al. · Nature Medicine · 2003 · 309 citations

Novel Viral Mechanism, Sarcoma–associated Herpesvirus Latency, Pathogenesis +8

Spindle Cell Conversion by Kaposi's Sarcoma-Associated Herpesvirus: Formation of Colonies and Plaques with Mixed Lytic and Latent Gene Expression in Infected Primary Dermal Microvascular Endothelial Cell Cultures

D M Ciufo, Jennifer S. Cannon, Lynn Poole et al. · Journal of Virology · 2001 · 186 citations · Full text

Origin-Independent Assembly of Kaposi's Sarcoma-Associated Herpesvirus DNA Replication Compartments in Transient Cotransfection Assays and Association with the ORF-K8 Protein and Cellular PML

Frederick Y. Wu, Jin‐Hyun Ahn, Donald J. Alcendor et al. · Journal of Virology · 2001 · 162 citations · Full text

Viral Replication, Viral Polymerase Mechanism, Immunology +19

Phospholipase Cγ1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE

Keqiang Ye, Bahman Aghdasi, Hongbo R. Luo et al. · Nature · 2002 · 155 citations

Protein Function, Signal Transduction, Molecular Regulation +11