Frederick Y. Wu

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

Shizhen Emily Wang, Archana Narasanna, Marianela Pérez-Torres et al. · Cancer Cell · 2006 · 468 citations · Full text

Medicine, Cancer Biology, Oncology +16

A novel viral mechanism for dysregulation of β-catenin in Kaposi's sarcoma–associated herpesvirus latency

Masahiro Fujimuro, Frederick Y. Wu, Colette Aprhys et al. · Nature Medicine · 2003 · 311 citations

Life Sciences, Infectious Diseases, Oncology +15

Spindle Cell Conversion by Kaposi's Sarcoma-Associated Herpesvirus: Formation of Colonies and Plaques with Mixed Lytic and Latent Gene Expression in Infected Primary Dermal Microvascular Endothelial Cell Cultures

D M Ciufo, Jennifer S. Cannon, Lynn Poole et al. · Journal of Virology · 2001 · 187 citations · Full text

Life Sciences, Cell Biology, Infectious Diseases +17

Origin-Independent Assembly of Kaposi's Sarcoma-Associated Herpesvirus DNA Replication Compartments in Transient Cotransfection Assays and Association with the ORF-K8 Protein and Cellular PML

Frederick Y. Wu, Jin‐Hyun Ahn, Donald J. Alcendor et al. · Journal of Virology · 2001 · 163 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Phospholipase Cγ1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE

Keqiang Ye, Bahman Aghdasi, Hongbo R. Luo et al. · Nature · 2002 · 156 citations

Life Sciences, Biochemistry, Molecular Biology +8