Bin Xiang

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

Shizhen Emily Wang, Archana Narasanna, Marianela Pérez-Torres et al. · Cancer Cell · 2006 · 464 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +8

ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome

Shigeki Iwase, Bin Xiang, Sharmistha Ghosh et al. · Nature Structural & Molecular Biology · 2011 · 257 citations

Atrx Add, Chromatin, Human Mental-retardation Syndrome +8

Transforming Growth Factor β Engages TACE and ErbB3 To Activate Phosphatidylinositol-3 Kinase/Akt in ErbB2-Overexpressing Breast Cancer and Desensitizes Cells to Trastuzumab

Shizhen Emily Wang, Bin Xiang, Marta Guix et al. · Molecular and Cellular Biology · 2008 · 168 citations · Full text

Signal Transduction, Signaling Pathway, Gene Signature +15

Transforming Growth Factor β Induces Clustering of HER2 and Integrins by Activating Src-Focal Adhesion Kinase and Receptor Association to the Cytoskeleton

Shizhen Emily Wang, Bin Xiang, Roy Zent et al. · Cancer Research · 2009 · 131 citations · Full text

ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression

Kajan Ratnakumar, Luís Duarte, Gary LeRoy et al. · Genes & Development · 2012 · 131 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +20