Concepedia

VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation

Jun Huang, J Chen

Oncogene · 2008 · 70 citations · 27 references

DOI

Concepts

References

27

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

Guy A. Rouleau, P. Merel, Mohini Lutchman et al. · Nature · 1993 · 1.4K citations

, , +9

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

James A. Trofatter · Cell · 1993 · 1.4K citations · Full text

, , +5

Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery

Stéphane Angers, Ti Li, Xianhua Yi et al. · Nature · 2006 · 667 citations

, , +12

A Family of Diverse Cul4-Ddb1-Interacting Proteins Includes Cdt2, which Is Required for S Phase Destruction of the Replication Factor Cdt1

Jianping Jin, Emily E. Arias, Jing Chen et al. · Molecular Cell · 2006 · 640 citations · Full text

, , +10

CUL4–DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation

Leigh Ann Higa, Min Wu, Ye Tao et al. · Nature Cell Biology · 2006 · 416 citations

, , +9