Polymorphisms in human soluble epoxide hydrolase: effects on enzyme activity, enzyme stability, and quaternary structure

Anti-inflammatory Properties of Cytochrome P450 Epoxygenase-Derived Eicosanoids

Koichi Node, Yuqing Huo, Xiu-Lu Ruan et al. · Science · 1999 · 1.2K citations

Veterinary Medicine, Cell Biology, Pharmacology +17

Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture.

Ziad Abdel‐Razzak, Pascal Loyer, Alain Fautrel et al. · Molecular Pharmacology · 1993 · 535 citations

Medicine, Biochemistry, Pharmacology +17

Targeted Disruption of Soluble Epoxide Hydrolase Reveals a Role in Blood Pressure Regulation

Christopher J. Sinal, Masaaki Miyata, Masahiro Tohkin et al. · Journal of Biological Chemistry · 2000 · 341 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Detoxification of environmental mutagens and carcinogens: Structure, mechanism, and evolution of liver epoxide hydrolase

M.A. Argiriadi, Christophe Morisseau, Bruce D. Hammock et al. · Proceedings of the National Academy of Sciences · 1999 · 226 citations

Life Sciences, Biochemistry, Molecular Biology +17

Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase.

Darryl C. Zeldin, Jun Kobayashi, John R. Falck et al. · Journal of Biological Chemistry · 1993 · 222 citations · Full text

Life Sciences, Biochemistry, Enzyme Mechanism +14