Enzyme Activity Polymorphism is a genetic variation in the coding sequence or regulatory regions of a gene encoding a drug-metabolizing enzyme that results in distinct, heritable differences in the enzyme's catalytic activity among individuals.
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A functional polymorphism in the monoamine oxidase A gene promoter
Sue Z. Sabol, Stella Hu, Dean H. Hamer · Human Genetics · 1998 · 1.1K citations · Full text
The molecular basis of the human serum paraoxonase activity polymorphism
Richard Humbert, David A. Adler, Christine M. Distèche et al. · Nature Genetics · 1993 · 840 citations
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