Richard M. Weinshilboum

Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders

Herbert M. Lachman, Demitri F. Papolos, Takuya Saito et al. · Pharmacogenetics · 1996 · 1.8K citations

Medicine, Genetics, Molecular Genetics +16

Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity.

Richard M. Weinshilboum, S. L. Sladek · PubMed · 1980 · 1.2K citations

Veterinary Medicine, Genetics, Pharmacology +13

CYP2D6 Genotype, Antidepressant Use, and Tamoxifen Metabolism During Adjuvant Breast Cancer Treatment

Zeruesenay Desta, Vered Stearns, Brent B. Ward et al. · JNCI Journal of the National Cancer Institute · 2005 · 942 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia

Lynne Lennard, J S Lilleyman, Jon Van Loon et al. · The Lancet · 1990 · 659 citations

Life Sciences, Genetics, Pediatrics +9

The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen

Matthew P. Goetz, Stacey K. Knox, Vera J. Suman et al. · Breast Cancer Research and Treatment · 2006 · 550 citations

Medicine, Pharmacokinetics, Pharmacology +14