Concepedia

Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians

Shruti Sharma, Mitashree Das, Ashok Kumar, Vishal Marwaha, Subramanian Shankar, Paramjeet Singh, Padmanabhan Raghu, Ritu Aneja, Rahul Grover, Vivek Arya,

Pharmacogenetics and Genomics · 2009 · 68 citations · 32 references

DOI

Abstract

Genes from all the three pathways seem to contribute to MTX response in the Indian population. However, these observations need to be replicated in an independent sample set.

References

32

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A New Statistical Method for Haplotype Reconstruction from Population Data

Matthew Stephens, Nicholas Smith, Peter Donnelly · The American Journal of Human Genetics · 2001 · 7.5K citations · Full text

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A "Silent" Polymorphism in the <i>MDR</i> 1 Gene Changes Substrate Specificity

Chava Kimchi‐Sarfaty, Jung Mi Oh, In‐Wha Kim et al. · Science · 2006 · 2.4K citations · Full text

A Comparison of Etanercept and Methotrexate in Patients with Early Rheumatoid Arthritis

Joan M. Bathon, Richard W. Martin, Roy Fleischmann et al. · New England Journal of Medicine · 2000 · 1.8K citations · Full text

Treatment of Active Rheumatoid Arthritis With Leflunomide Compared With Placebo and Methotrexate

Vibeke Strand · Archives of Internal Medicine · 1999 · 752 citations