Concepedia

A transgenic mouse model for monitoring endoplasmic reticulum stress

Takao Iwawaki, Ryoko Akai, Kenji Kohno, Masayuki Miura

Nature Medicine · 2003 · 474 citations · 21 references

DOI

Concepts

References

21

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Hiderou Yoshida, Toshie Matsui, Akira Yamamoto et al. · Cell · 2001 · 4.1K citations · Full text

, , +13

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

Toshiyuki Nakagawa, Hong Zhu, Nobuhiro Morishima et al. · Nature · 2000 · 3.3K citations

, , +12

Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells

Heather P. Harding, Isabel Novoa, Yuhong Zhang et al. · Molecular Cell · 2000 · 3.2K citations · Full text

, , +12

Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1

Fumihiko Urano, Xiao-Zhong Wang, Anne Bertolotti et al. · Science · 2000 · 3K citations

, , +16

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

Marcella A. Calfon, Huiqing Zeng, Fumihiko Urano et al. · Nature · 2002 · 2.9K citations

, , +5