Concepedia

Transgenic Model Generation

Transgenic Model Generation is a methodological framework within genetic engineering that enables the creation of organisms harboring exogenous DNA sequences, such as yeast artificial chromosomes, to study gene function and regulatory mechanisms in a controlled, heritable manner.

378

Publications

28.4K

Citations

2.9K

Authors

809

Institutions

Publications per year

2017–2026

54

Parents

Publications

378

In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker

Noboru Mizushima, Akitsugu Yamamoto, Makoto Matsui et al. · Molecular Biology of the Cell · 2003 · 2.3K citations · Full text

, , +13

A transgenic zebrafish model of neutrophilic inflammation

Stephen A. Renshaw, Catherine A. Loynes, Daniel M.I. Trushell et al. · Blood · 2006 · 1K citations · Full text

, , +13

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

Taoufiq Harach, Nittaya Marungruang, N. Duthilleul et al. · Scientific Reports · 2017 · 913 citations · Full text

, , +17

Age-Dependent Neurofibrillary Tangle Formation, Neuron Loss, and Memory Impairment in a Mouse Model of Human Tauopathy (P301L)

Martin Ramsden, Linda Kotilinek, Colleen L. Forster et al. · Journal of Neuroscience · 2005 · 719 citations · Full text

, , +17

Towards a transgenic model of Huntington’s disease in a non-human primate

Shang‐Hsun Yang, Pei-Hsun Cheng, Heather Banta et al. · Nature · 2008 · 508 citations · Full text

, , +14

1–5 of 378

Authors

2.9K

  1. ER
    Edward Rockenstein

    University of California San Diego, United States

    4 publications · 433 citations

    4

    h-index

  2. HP
    Huu Phuc Nguyen

    University of Tübingen, Germany

    4 publications · 524 citations

    4

    h-index

  3. MB
    Michael Bäder

    Max Delbrück Center, Germany

    4 publications · 421 citations

    4

    h-index

  4. SM
    Shuichiro Maeda

    Kumamoto University, Japan

    4 publications · 130 citations

    4

    h-index

  5. MM
    Michael Mante

    University of California San Diego, United States

    4 publications · 433 citations

    4

    h-index

1–5 of 2.9K

Institutions

809

  1. Harvard University

    Cambridge, United States

    12 h-index

    44 publications

    4.5K citations

  2. University of Pennsylvania

    Philadelphia, United States

    11 h-index

    35 publications

    4.3K citations

  3. Inserm

    Paris, France

    9 h-index

    49 publications

    2.9K citations

  4. University of Washington

    Seattle, United States

    8 h-index

    25 publications

    3.8K citations

  5. Baylor College of Medicine

    Houston, United States

    8 h-index

    45 publications

    4.2K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    20 publications

    2K citations

  7. University of Minnesota

    Minneapolis, United States

    7 h-index

    23 publications

    4.7K citations

  8. University of Oxford

    Oxford, United Kingdom

    7 h-index

    35 publications

    1.6K citations

1–8 of 809

Venues

  1. PubMed

    Repository · 18 publications · 1.5K citations

    15

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 14 publications · 1.9K citations

    14

    h-index

  3. PLoS ONE

    17 publications · 386 citations

    14

    h-index

  4. The Journal of Immunology

    JI · 10 publications · 581 citations

    10

    h-index

  5. Scientific Reports

    9 publications · 1.2K citations

    9

    h-index

1–5