Recombinant protein production in Pichia pastoris under glyceraldehyde-3-phosphate dehydrogenase promoter: From carbon source metabolism to bioreactor operation parameters

The codon adaptation index-a measure of directional synonymous codon usage bias, and its potential applications

Paul M. Sharp, Wen‐Hsiung Li · Nucleic Acids Research · 1987 · 4.1K citations · Full text

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Genome sequence of the recombinant protein production host Pichia pastoris

Kristof De Schutter, Yao‐Cheng Lin, Petra Tiels et al. · Nature Biotechnology · 2009 · 545 citations · Full text

Life Sciences, Biotechnology, Microbiology +13

Isolation of the Pichia pastoris glyceraldehyde-3-phosphate dehydrogenase gene and regulation and use of its promoter

Hans R. Waterham, Mary Ellen Digan, P J Koutz et al. · Gene · 1997 · 441 citations

Life Sciences, Genetics, Molecular Biology +8

Strategies for optimal synthesis and secretion of heterologous proteins in the methylotrophic yeast Pichia pastoris

Koti Sreekrishna, Robert G. Brankamp, Keith E. Kropp et al. · Gene · 1997 · 437 citations

Life Sciences, Biotechnology, Molecular Biology +16

Gene expression from plasmids containing the <i>araBAD</i> promoter at subsaturating inducer concentrations represents mixed populations

Deborah A. Siegele, James C. Hu · Proceedings of the National Academy of Sciences · 1997 · 426 citations · Full text

Life Sciences, Genetics, Microbiology +17