Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

William E. Dowdle, Beat Nyfeler, Jane Nagel, +44

Nature Cell Biology

InflammationCell AutophagySignal TransductionHeme HomeostasisIron Metabolism +11

Isolation of the Pichia pastoris glyceraldehyde-3-phosphate dehydrogenase gene and regulation and use of its promoter

Hans R. Waterham, Mary Ellen Digan, P J Koutz, +2

Gene

Transcriptional RegulationCellular EnzymologyBiochemistryNatural SciencesGenetics +5

Genetic and molecular analysis of fs(1)h, a maternal effect homeotic gene in Drosophila

Mary Ellen Digan, Susan R. Haynes, Brian A. Mozer, +3

Developmental Biology

BiologyDevelopmental BiologyDevelopmental GeneticsGeneticsMolecular Analysis +8

Two clusters of genes for major chorion proteins of Drosophila melanogaster

Allan C. Spradling, Mary Ellen Digan, Anthony P. Mahowald, +2

Cell

Drosophila MelanogasterSystems BiologyMajor Chorion ProteinsGeneticsGenomic Mechanism +7

Continuous Production of a Novel Lysozyme via Secretion from the Yeast, Pichia pastoris

Mary Ellen Digan, Stephen V. Lair, R. A. Brierley, +9

Nature Biotechnology

BiomanufacturingEngineeringMedicineBiochemical EngineeringBiotechnology +8

The Tyrosine Phosphatase PTPN14 Is a Negative Regulator of YAP Activity

Chrysiis Michaloglou, Waltraut Lehmann, Typhaine Martin, +15

PLoS ONE

Negative RegulatorMolecular RegulationPtpn14 Ppxy MotifCell DeathTumor Biology +16

A family of oligo-adenylate-terminated transposable sequences in Drosophila melanogaster

Pier Paolo Di Nocera, Mary Ellen Digan, Igor B. Dawid

Journal of Molecular Biology

Drosophila MelanogasterGeneticsGenomic MechanismMolecular BiologyGene Structure +2

Drosophila melanogaster homologs of the raf oncogene.

G E Mark, Ross MacIntyre, Mary Ellen Digan, +2

Molecular and Cellular Biology

GeneticsGenomic MechanismMolecular GeneticsGenomicsDrosophila Melanogaster Dna +14

Improved binding of a bivalent single-chain immunotoxin results in increased efficacy for in vivo T-cell depletion

Jerry Thompson, Scott Stavrou, Marla Weetall, +11

Protein Engineering Design and Selection

Activation of human STING by a molecular glue-like compound

Jie Li, Stephen M. Canham, Hua Wu, +32

Nature Chemical Biology