Koti Sreekrishna

Strategies for optimal synthesis and secretion of heterologous proteins in the methylotrophic yeast Pichia pastoris

Koti Sreekrishna, Robert G. Brankamp, Keith E. Kropp et al. · Gene · 1997 · 436 citations

Biosynthesis, Engineering, Biochemistry +10

High-Level Expression of Tetanus Toxin Fragment C in Pichia Pastoris Strains Containing Multiple Tandem Integrations of the Gene

Jeff J. Clare, F. B. Rayment, S. Ballantine et al. · Nature Biotechnology · 1991 · 393 citations · Full text

Microbial Toxin, Biosynthesis, Engineering +6

Production of mouse epidermal growth factor in yeast: high-level secretion using Pichia pastoris strains containing multiple gene copies

Jeffrey J. Clare, Michael A. Romanes, F. B. Rayment et al. · Gene · 1991 · 331 citations

Engineering, Genetics, Biotechnology +10

Rapid Selection Using G418 of High Copy Number Transformants of Pichia pastoris for High–level Foreign Gene Expression

Carol A. Scorer, Jeffrey J. Clare, W. Richard McCombie et al. · Nature Biotechnology · 1994 · 307 citations

Engineering, Genetics, Biotechnology +7

High-level expression, purification, and characterization of recombinant human tumor necrosis factor synthesized in the methylotrophic yeast Pichia pastoris

Koti Sreekrishna, Lynn P. Nelles, Rica Potenz et al. · Biochemistry · 1989 · 154 citations