Reduced telomere DNA content is correlated with genomic instability and metastasis in invasive human breast carcinoma

pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long‐term follow‐up

C.W. Elston, Ian O. Ellis · Histopathology · 1991 · 6.2K citations

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Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.7K citations

Education, Cell Biology, Genetics +11

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

Robert K. Moyzis, Judy M. Buckingham, L. Scott Cram et al. · Proceedings of the National Academy of Sciences · 1988 · 2.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Telomere length predicts replicative capacity of human fibroblasts.

Richard Allsopp, Homayoun Vaziri, Cam Patterson et al. · Proceedings of the National Academy of Sciences · 1992 · 2.2K citations · Full text

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Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

Christopher M. Counter, Ariel A. Avilion, Catherine LeFeuvre et al. · The EMBO Journal · 1992 · 2.1K citations · Full text

Life Sciences, Cell Biology, Genetics +14