Concepedia

The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity

Mirjam Kool, Geert Loo, Wim Waelput, Sofie De Prijck, Femke Muskens, Mozes Sze, Jens Van Praet, Filipe Branco‐Madeira, Sophie Janssens, Boris Reizis,

Immunity · 2011 · 253 citations · 39 references

DOIFull text

Open access

Concepts

References

39

IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

Liang Zhou, Ivaylo I. Ivanov, Rosanne Spolski et al. · Nature Immunology · 2007 · 2.1K citations

, , +16

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling

Ingrid E. Wertz, Karen O’Rourke, Honglin Zhou et al. · Nature · 2004 · 1.8K citations

, , +12

Failure to Regulate TNF-Induced NF-κB and Cell Death Responses in A20-Deficient Mice

Eric G. Lee, David L. Boone, Sophia Chai et al. · Science · 2000 · 1.4K citations · Full text

, , +17

Induction of Dendritic Cell Differentiation by IFN-α in Systemic Lupus Erythematosus

Patrick Blanco, A. Karolina Palucka, Michelle A. Gill et al. · Science · 2001 · 1.3K citations

, , +17

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

David L. Boone, Emre E. Turer, Eric G. Lee et al. · Nature Immunology · 2004 · 1.1K citations

, , +14