Roles for GP IIb/IIIa and αvβ3 integrins in MDA-MB-231 cell invasion and shear flow-induced cancer cell mechanotransduction

Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3

Peter C. Brooks, Staffan Strömblad, Luraynne C. Sanders et al. · Cell · 1996 · 1.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling

Junichi Takagi, Benjamin M. Petre, Thomas Walz et al. · Cell · 2002 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell–mediated elimination of tumor cells

Joseph S. Palumbo, Kathryn E. Talmage, Jessica V. Massari et al. · Blood · 2004 · 990 citations · Full text

Medicine, Cancer Biology, Oncology +14

Lysis of tumor cells by natural killer cells in mice is impeded by platelets.

Bernhard Nieswandt, Michael Häfner, Bernd Echtenacher et al. · PubMed · 1999 · 838 citations

Life Sciences, Immunology, Oncology +13

Integrin activation controls metastasis in human breast cancer

Brunhilde Felding‐Habermann, Timothy E. O’Toole, Jeffrey W. Smith et al. · Proceedings of the National Academy of Sciences · 2001 · 580 citations

Life Sciences, Cell Biology, Oncology +16