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Cytoplasmic p27Kip1 counteracts the pro-apoptotic function of the open conformation of PTEN by retention and destabilization of PTEN outside of the nucleus

Pro-apoptotic FunctionProtein FunctionSignal TransductionCytoplasmic P27kip1Cell RegulationNatural SciencesCell DeathMolecular BiologyOpen ConformationCellular BiochemistryMedicineCell BiologyCell SignalingCellular PhysiologyProtein Phosphorylation