Tenets of PTEN Tumor Suppression

Mutation and Cancer: Statistical Study of Retinoblastoma

Alfred G. Knudson · Proceedings of the National Academy of Sciences · 1971 · 7.6K citations · Full text

Life Sciences, Genetics, Oncology +16

A microRNA expression signature of human solid tumors defines cancer gene targets

Stefano Volinia, George A. Calin, Chang‐Gong Liu et al. · Proceedings of the National Academy of Sciences · 2006 · 5.7K citations · Full text

Medicine, Cancer Biology, Oncology +15

<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

Medicine, Molecular Genetics, Oncology +16

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations

Medicine, Oncology, Pharmacology +15

The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate

Tomohiko Maehama, Jack E. Dixon · Journal of Biological Chemistry · 1998 · 3.1K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17