Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids: different mechanisms of induction of beta cell death in vitro

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

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Life Sciences, Cell Biology, Molecular Biology +16

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

Yuri Lazebnik, Scott H. Kaufmann, Serge Desnoyers et al. · Nature · 1994 · 2.6K citations

Life Sciences, Biochemistry, Molecular Biology +10

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

Chutima Talchai, Shouhong Xuan, Hua Lin et al. · Cell · 2012 · 1.4K citations · Full text

Medicine, Cell Biology, Physiology +14

FoxO1 protects against pancreatic β cell failure through NeuroD and MafA induction

Yukari Kitamura, Tadahiro Kitamura, Jan-Philipp Kruse et al. · Cell Metabolism · 2005 · 561 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth

Tadahiro Kitamura, Jun Nakae, Yukari Kitamura et al. · Journal of Clinical Investigation · 2002 · 539 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +14