Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction

Pere Puigserver, James Rhee, Jerry Donovan, +8

Nature

MedicineLiver PhysiologyDiabetesMetabolic RegulationMetabolism +5

The Forkhead Transcription Factor Foxo1 Regulates Adipocyte Differentiation

Jun Nakae, Tadahiro Kitamura, Yukari Kitamura, +3

Developmental Cell

Transcriptional RegulationGeneticsGene RegulationMetabolic RegulationGene Expression +2

FoxO1 protects against pancreatic β cell failure through NeuroD and MafA induction

Yukari Kitamura, Tadahiro Kitamura, Jan-Philipp Kruse, +4

Cell Metabolism

Developmental BiologyMafa InductionPancreatic CancerCell DeathPancreas Transplantation +4

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth

Tadahiro Kitamura, Jun Nakae, Yukari Kitamura, +6

Journal of Clinical Investigation

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth

Tadahiro Kitamura, Jun Nakae, Yukari Kitamura, +6

Journal of Clinical Investigation

Pdx1 RegulationInsulin SignalingType 1Transcriptional RegulationSignaling Pathway +15

Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake

Tadahiro Kitamura, Yun Feng, Yukari Kitamura, +5

Nature Medicine

BiologyNutritionForkhead Protein Foxo1Appetite ControlAgrp-dependent Effects +6

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells.

Kenta Hara, Kazuyoshi Yonezawa, Hiroshi Sakaue, +7

Proceedings of the National Academy of Sciences

Complex FormationInsulin SignalingCellular PhysiologySignaling PathwayReceptor Tyrosine Kinase +18

Insulin-Induced Phosphorylation and Activation of Cyclic Nucleotide Phosphodiesterase 3B by the Serine-Threonine Kinase Akt

Tadahiro Kitamura, Yukari Kitamura, Shoji Kuroda, +8

Molecular and Cellular Biology

Serine-threonine Kinase AktMouse Pde3bSignal TransductionMolecular PhysiologyBiochemistry +13

Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling.

K. Kotani, Kouichiro Yonezawa, Kenta Hara, +7

The EMBO Journal

Developmental BiologySignal TransductionMolecular PhysiologySignaling PathwayCell Signaling +8

A Foxo/Notch pathway controls myogenic differentiation and fiber type specification

Tadahiro Kitamura, Yukari Kitamura, Yasuhiro Funahashi, +6

Journal of Clinical Investigation

Muscle FunctionGeneticsFoxo/notch PathwayMolecular GeneticsCellular Physiology +17