Dietary squalene supplementation improves DSS‐induced acute colitis by downregulating p38 MAPK and NFkB signaling pathways

Abstract

Squalene was able to improve the oxidative events and returned proinflammatory proteins expression to basal levels probably through p38 mitogen-activated protein kinase and nuclear factor-kappa B signaling pathways. However, supplementary studies are needed in order to provide a basis for developing a new dietary supplementation strategy.