Serine in plants: biosynthesis, metabolism, and functions

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

Richard Possemato, Kevin M. Marks, Yoav D. Shaul et al. · Nature · 2011 · 1.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

<scp>d</scp> -Serine is an endogenous ligand for the glycine site of the <i>N</i> -methyl- <scp>d</scp> -aspartate receptor

Jean‐Pierre Mothet, Angèle Parent, Herman Wolosker et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Jason W. Locasale, Alexandra Grassian, Tamar Melman et al. · Nature Genetics · 2011 · 1.1K citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +13

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

Oliver D.K. Maddocks, Celia R. Berkers, Susan Mason et al. · Nature · 2012 · 1K citations

Life Sciences, Cancer Biology, Oncology +16

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

Barbara Chaneton, Petra Hillmann, Liang Zheng et al. · Nature · 2012 · 665 citations

Life Sciences, Biochemistry, Molecular Biology +9