Publication | Closed Access

The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA

ChromatinCatalytic DomainN-terminal PartBiochemistryNatural SciencesEpigenetic ChangeDna MethylationEpigenomicsMolecular BiologyDna ReplicationOligonucleotideAllosteric ActivationDna DemethylationGene ExpressionMedicineEpigeneticsTranscription Regulation