Concepedia

Gene therapy for red–green colour blindness in adult primates

Katherine Mancuso, William W. Hauswirth, Qiuhong Li, Thomas B. Connor, James A. Kuchenbecker, Matthew C. Mauck, Jay Neitz, Maureen Neitz

Nature · 2009 · 347 citations · 16 references

Open access

Concepts

MedicineBiotechnologyVision ScienceGene DeliveryGene TherapyGenetic EngineeringColor BlindnessColor Vision DeficiencyOcular Gene DeliveryOcular Gene TherapyRetinal Pigment EpitheliumVisual ImpairmentColor Vision Gene TherapyGene-targeted TherapyOptogenetic Gene TherapyOptogenetic TherapyRed-green Color BlindnessRed-green Color DeficiencyRed-green Color Vision Deficiency

References

16

SINGLE-CELL RESPONSES IN STRIATE CORTEX OF KITTENS DEPRIVED OF VISION IN ONE EYE

Torsten N. Wiesel, David H. Hubel · Journal of Neurophysiology · 1963 · 2.6K citations · Full text

Medicine, Neurobiology, Neuroscience +9

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

Albert M. Maguire, Francesca Simonelli, Eric A. Pierce et al. · New England Journal of Medicine · 2008 · 2.1K citations · Full text

Medicine, Genetics, Ophthalmology +17

Molecular Genetics of Human Color Vision: The Genes Encoding Blue, Green, and Red Pigments

Jeremy Nathans, Darcy Thomas, David S. Hogness · Science · 1986 · 1.7K citations

Medicine, Genetics, Molecular Genetics +10

Molecular Genetics of Inherited Variation in Human Color Vision

Jeremy Nathans, Thomas P. Piantanida, Roger L. Eddy et al. · Science · 1986 · 785 citations

Medicine, Genetics, Molecular Genetics +17

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

Artur V. Cideciyan, Tomás S. Alemán, Sanford L. Boye et al. · Proceedings of the National Academy of Sciences · 2008 · 664 citations · Full text

Medicine, Genetics, Ophthalmology +17