Sanford L. Boye

Treatment of Leber Congenital Amaurosis Due to <i>RPE65</i> Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial

William W. Hauswirth, Tomás S. Alemán, Shalesh Kaushal et al. · Human Gene Therapy · 2008 · 947 citations · Full text

Medicine, Molecular Biology, Ophthalmology +15

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

Artur V. Cideciyan, Tomás S. Alemán, Sanford L. Boye et al. · Proceedings of the National Academy of Sciences · 2008 · 664 citations · Full text

Medicine, Genetics, Ophthalmology +17

Human <i>RPE65</i> Gene Therapy for Leber Congenital Amaurosis: Persistence of Early Visual Improvements and Safety at 1 Year

Artur V. Cideciyan, William W. Hauswirth, Tomás S. Alemán et al. · Human Gene Therapy · 2009 · 312 citations · Full text

Medicine, Immunology, Ophthalmology +17

Virally delivered Channelrhodopsin-2 Safely and Effectively Restores Visual Function in Multiple Mouse Models of Blindness

M. Mehdi Doroudchi, Kenneth P. Greenberg, Jianwen Liu et al. · Molecular Therapy · 2011 · 277 citations · Full text

Medicine, Neurobiology, Neuroscience +16

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death

Derek S. Welsbie, Zhiyong Yang, Yan Ge et al. · Proceedings of the National Academy of Sciences · 2013 · 271 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17