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Synthesis and optimization of an original V-shaped collection of 4-7-disubstituted Pyrido[3,2-d]pyrimidines as CDK5 and DYRK1A inhibitors

Combinatorial ChemistryMedicinal ChemistryBiochemistryNatural SciencesMedicineDiversity-oriented SynthesisRational Drug DesignOriginal V-shaped CollectionHeterocycle ChemistryPharmacologyDyrk1a InhibitorsDrug Discovery