M. Soundararajan

Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function

Nicholas Kwiatkowski, Nannette Jelluma, P. Filippakopoulos et al. · Nature Chemical Biology · 2010 · 231 citations · Full text

Tumor Biology, Signal Transduction, Small-molecule Kinase Inhibitors +14

Structural diversity in the RGS domain and its interaction with heterotrimeric G protein α-subunits

M. Soundararajan, Francis S. Willard, Adam J. Kimple et al. · Proceedings of the National Academy of Sciences · 2008 · 209 citations · Full text

Protein Assembly, Rgs Domain, Galpha Subunits +17

Selectivity, Cocrystal Structures, and Neuroprotective Properties of Leucettines, a Family of Protein Kinase Inhibitors Derived from the Marine Sponge Alkaloid Leucettamine B

Tania Tahtouh, Jonathan M. Elkins, P. Filippakopoulos et al. · Journal of Medicinal Chemistry · 2012 · 184 citations · Full text

Dual Specificity, Drug Target, Kinase Inhibitors +21

Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition

M. Soundararajan, A.K. Roos, P. Savitsky et al. · Structure · 2013 · 154 citations · Full text

Leucettines, a Class of Potent Inhibitors of cdc2-Like Kinases and Dual Specificity, Tyrosine Phosphorylation Regulated Kinases Derived from the Marine Sponge Leucettamine B: Modulation of Alternative Pre-RNA Splicing

Mansour Debdab, François Carreaux, Stéven Renault et al. · Journal of Medicinal Chemistry · 2011 · 144 citations · Full text

Dual Specificity, Rna Splicing, Kinase Inhibitors +19