Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells - Concepedia

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Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells

DOI Full Paper Access

29

Citations

23

References

2010

Year

Zekuan Xu, Yi Zhang, Jiakai Jiang, Yang Yang, Ruihua Shi, Bo Hao, Zhihong Zhang, Zuhu Huang, Jin W. Kim, Guoxin Zhang

Abstract

EGF-induced HCCR-1 over-expression is mediated by PI3K/AKT/mTOR signaling which plays a pivotal role in pancreatic tumor progression, suggesting that HCCR-1 could be a potential target for cancer therapeutics.

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