Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis..

Hywel C Williams, Roderick J. Hay, Corey Archer et al. · British Journal of Dermatology · 1994 · 1.3K citations

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Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

Paul Van Eerdewegh, Randall D. Little, Josée Dupuis et al. · Nature · 2002 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +14

Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris

Frances J.D. Smith, Alan D. Irvine, Ana Terron-Kwiatkowski et al. · Nature Genetics · 2006 · 1K citations

Life Sciences, Genetics, Molecular Genetics +9

The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis. III. Independent hospital validation

Hywel C Williams, A.C. Pembroke, Roderick J. Hay · British Journal of Dermatology · 1994 · 930 citations

Medicine, Dermatology, Pediatrics +14

Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice.

Jonathan M. Spergel, Emiko Mizoguchi, Joanne P. Brewer et al. · Journal of Clinical Investigation · 1998 · 637 citations · Full text

Life Sciences, Dermatology, Immunology +17