Alan D. Irvine - Concepedia

Author

Alan D. Irvine

Also Known As

A D Irvine, A De Surgy, A Irvine, A. D. IRVINE, A. D. Irvine, A. IRVINE, A. Irvine, A.D. IRVINE, A.D. Irvine, A.S. Irvine

621

Publications

37K

Citations

H-Index

190

Concepts

All Affiliations

Trinity College Dublin Our Lady's Hospital Children's Health Ireland at Crumlin National Children’s Research Centre University of Dundee

About

Alan D. Irvine is an author at Trinity College Dublin specializing in medicine, dermatology, and genetics.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	44	72	14.4K
2	Education	3	3	122
3	Engineering	1	1	14
4	Health Sciences	1	1	170
5	Natural Sciences	1	1	208

Alan D. Irvine

186

Publications

22.6K

Citations

H-Index

Page 1

	Year	Citations
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis Alan D. Irvine, Ana Terron-Kwiatkowski, Yiwei Zhao, Nature Genetics Major Predisposing FactorCommon Loss-of-function VariantsAtopic DermatitisCutaneous BiologyImmunology	2006	2.9K
Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris Frances J.D. Smith, Alan D. Irvine, Ana Terron-Kwiatkowski, Nature Genetics BiologyMendelian DisorderGenetic DisorderGeneticsPathogenesis	2006	1K
Filaggrin in the frontline: role in skin barrier function and disease Aileen Sandilands, Calum Sutherland, Alan D. Irvine, Journal of Cell Science Atopic EczemaCytoskeletonSerine ProteasesDermatologyExperimental Dermatology	2009	849
Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome Stéphane Chavanas, Christine Bodemer, Ariane Rochat, Nature Genetics Mendelian DisorderGenetic DisorderGeneticsMolecular BiologySerine Protease Inhibitor	2000	838
Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema Aileen Sandilands, Ana Terron-Kwiatkowski, Peter Hull, Nature Genetics AllergyAtopic DermatitisGenetic DisorderGeneticsPathogenesis	2007	660
Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations Stephan Weidinger, Thomas Illig, Hansjörg Baurecht, Journal of Allergy and Clinical Immunology Filaggrin Gene PredisposeAllergyAtopic DermatitisGeneticsAllergen	2006	608
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation Alexander Hooftman, Stefano Angiari, Svenja Hester, Cell Metabolism InflammationAnti-inflammatorySignal TransductionAutoimmune DiseaseImmunology	2020	542
Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials Emma Guttman‐Yassky, Henrique D. Teixeira, Eric L. Simpson, The Lancet AllergyUpadacitinib Versus PlaceboAtopic DermatitisAllergy MedicineClinical Trials	2021	502
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming Padraic G. Fallon, Takashi Sasaki, Aileen Sandilands, Nature Genetics Knockout MouseAllelic VariantDevelopmental BiologySomatic VariantHomozygous Frameshift Mutation	2009	470
Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy Sara Brown, Yuka Asai, Heather J. Cordell, Journal of Allergy and Clinical Immunology	2011	466

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