Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer - Concepedia

Concepedia

Publication | Open Access

Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer

DOI Full Paper Access

161

Citations

50

References

2011

Year

George Philips, Isaac S. Chan, Marzena Swiderska, Vanessa T. Schroder, Cynthia D. Guy, Gamze Karaca, Cynthia A. Moylan, Talaignair N. Venkatraman, Sebastian Feuerlein, Wing‐Kin Syn,

Abstract

Hh pathway activation promotes liver fibrosis and hepatocarcinogenesis, and inhibiting Hh signaling safely reverses both processes even when fibrosis and HCC are advanced.

References

	Year	Citations

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