Concepedia

The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells

Célia Rosilio, Nadia Lounnas, Marielle Nebout, Véronique Imbert, Thijs J. Hagenbeek, Hergen Spits, Vahid Asnafi, Rodolphe Pontier-Bres, Julie Reverso, J.F. Michiels,

Cancer Letters · 2013 · 67 citations · 31 references

DOI

Concepts

References

31

Role of AMP-activated protein kinase in mechanism of metformin action

Gaochao Zhou, Robert P. Myers, Ying Li et al. · Journal of Clinical Investigation · 2001 · 5.4K citations

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The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

Maria M. Mihaylova, Reuben J. Shaw · Nature Cell Biology · 2011 · 2.9K citations · Full text

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Peter A. Steck, Mark A. Pershouse, Samar A. Jasser et al. · Nature Genetics · 1997 · 2.8K citations

, , +11

Metformin and reduced risk of cancer in diabetic patients

Josie Evans, Louise A. Donnelly, Alistair Emslie‐Smith et al. · BMJ · 2005 · 2.4K citations · Full text

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Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

Arkaitz Carracedo, Li Ma, Julie Teruya‐Feldstein et al. · Journal of Clinical Investigation · 2008 · 1.4K citations · Full text

, , +17