Concepedia

Fluorescence assay of SIRT protein deacetylases using an acetylated peptide substrate and a secondary trypsin reaction

Patrick A. Marcotte, Paul R. Richardson, Jun Guo, Leo W. Barrett, Nan Xu, Angelo Gunasekera, Keith B. Glaser

Analytical Biochemistry · 2004 · 83 citations · 25 references

DOI

Concepts

References

25

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Shin‐ichiro Imai, Christopher M. Armstrong, Matt Kaeberlein et al. · Nature · 2000 · 3.5K citations

, , +16

hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

Homayoun Vaziri, Scott Dessain, Elinor Ng Eaton et al. · Cell · 2001 · 2.6K citations · Full text

, , +8

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

Wei Gu, R G Roeder · Cell · 1997 · 2.6K citations · Full text

, , +12

Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

Jianyuan Luo, Anatoly Nikolaev, Shin‐ichiro Imai et al. · Cell · 2001 · 2.1K citations · Full text

, , +14

Phylogenetic Classification of Prokaryotic and Eukaryotic Sir2-like Proteins

Roy A. Frye · Biochemical and Biophysical Research Communications · 2000 · 1.4K citations

, , +13