Roy A. Frye

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Fan Yeung, Jamie E. Hoberg, C S Ramsey et al. · The EMBO Journal · 2004 · 2.7K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

Homayoun Vaziri, Scott Dessain, Elinor Ng Eaton et al. · Cell · 2001 · 2.6K citations · Full text

Life Sciences, Genetics, Molecular Biology +8

Phylogenetic Classification of Prokaryotic and Eukaryotic Sir2-like Proteins

Roy A. Frye · Biochemical and Biophysical Research Communications · 2000 · 1.4K citations

Life Sciences, Genetics, Molecular Biology +13

Characterization of Five Human cDNAs with Homology to the Yeast SIR2 Gene: Sir2-like Proteins (Sirtuins) Metabolize NAD and May Have Protein ADP-Ribosyltransferase Activity

Roy A. Frye · Biochemical and Biophysical Research Communications · 1999 · 805 citations

Life Sciences, Biochemistry, Molecular Biology +7

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.

John P. O’Bryan, Roy A. Frye, Patricia C. Cogswell et al. · Molecular and Cellular Biology · 1991 · 723 citations · Full text

Medicine, Molecular Biology, Molecular Genetics +13