N-Hydroxy-(4-oxime)-cinnamide: A versatile scaffold for the synthesis of novel histone deacetilase (HDAC) inhibitors

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Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101.

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Histone Modifications, Colon Tumor Xenografts, Chemoprevention Strategy +18

HDAC inhibitors overcome first hurdle

Ken Garber · Nature Biotechnology · 2007 · 92 citations

Hdac Inhibitors, Pharmacology, Pharmacotherapy +4

Identification of Phenylisoxazolines as Novel and Viable Antibacterial Agents Active against Gram-Positive Pathogens

Michael R. Barbachyn, Gary J. Cleek, Lester A. Dolak et al. · Journal of Medicinal Chemistry · 2002 · 88 citations

Bioorganic Chemistry, Antibacterial Activity, Antimicrobial Chemotherapy +17

Synthesis and Biological Properties of Novel, Uracil-Containing Histone Deacetylase Inhibitors

Antonello Mai, Silvio Massa, Dante Rotili et al. · Journal of Medicinal Chemistry · 2006 · 55 citations · Full text

Histone Deacetylases, Medicinal Chemistry, Biochemistry +13