Lester A. Dolak

Tipranavir (PNU-140690):  A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class

Steve R. Turner, Joseph W. Strohbach, Rubén Tommasi et al. · Journal of Medicinal Chemistry · 1998 · 293 citations · Full text

Structure-Based Design of Novel HIV Protease Inhibitors: Carboxamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Nonpeptidic Inhibitors

Suvit Thaisrivongs, Keith David Watenpaugh, W. Jeffrey Howe et al. · Journal of Medicinal Chemistry · 1995 · 121 citations · Full text

Structure-Based Design of HIV Protease Inhibitors:  Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors

Suvit Thaisrivongs, Harvey I. Skulnick, Steve R. Turner et al. · Journal of Medicinal Chemistry · 1996 · 96 citations · Full text

Hiv Protease Inhibitors, Pharmacotherapy, Antiviral Drug +20

Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists

Daniel P. Walker, Donn G. Wishka, David W. Piotrowski et al. · Bioorganic & Medicinal Chemistry · 2006 · 94 citations

Structure–activity Relationship, Vivo Activity, Biochemistry +8

Identification of Phenylisoxazolines as Novel and Viable Antibacterial Agents Active against Gram-Positive Pathogens

Michael R. Barbachyn, Gary J. Cleek, Lester A. Dolak et al. · Journal of Medicinal Chemistry · 2002 · 88 citations

Bioorganic Chemistry, Antibacterial Activity, Antimicrobial Chemotherapy +17