Frequent requirement of hedgehog signaling in non-small cell lung carcinoma

Cancer statistics, 1999

Sarah Landis, Thomas S. Murray, S. Bolden et al. · CA A Cancer Journal for Clinicians · 1999 · 3.1K citations · Full text

Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer

Carla F. Bender Kim, Erica L. Jackson, Amber Woolfenden et al. · Cell · 2005 · 2.2K citations · Full text

Bronchioalveolar Stem Cells, Normal Lung, Medicine +7

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

Sarah P. Thayer, Marina Pasca di Magliano, Patrick W. Heiser et al. · Nature · 2003 · 1.5K citations · Full text

Tumor Biology, Oncology, Pancreatic Cancer +7

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

James Chen, Jussi Taipale, Michael K. Cooper et al. · Genes & Development · 2002 · 1.5K citations · Full text

Signal Transduction, Fluorescent Derivatives, Biochemistry +14

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Jussi Taipale, James Chen, Michael K. Cooper et al. · Nature · 2000 · 1.3K citations

Oncogenic Mutations, Gene Therapies, Genome Instability +8