Concepedia

Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons

Jakub Siednienko, Ruaidhrí Jackson, Mark Mellett, Nezira Delagic, Shuo Yang, Bingwei Wang, Lisa S. Tang, John J. Callanan, Bernard P. Mahon

Nature Immunology · 2012 · 58 citations · 40 references

DOI

Concepts

References

40

IKKε and TBK1 are essential components of the IRF3 signaling pathway

Katherine A. Fitzgerald, Sarah M. McWhirter, Daniel C. Rowe et al. · Nature Immunology · 2003 · 2.7K citations

, , +6

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

, , +5

MyD88 Is an Adaptor Protein in the hToll/IL-1 Receptor Family Signaling Pathways

Ruslan Medzhitov, Paula Preston‐Hurlburt, Elizabeth B. Kopp et al. · Molecular Cell · 1998 · 1.6K citations · Full text

, , +17

TRAF6 is a signal transducer for interleukin-1

Zhaodan Cao, Jessie Xiong, Masahiro Takeuchi et al. · Nature · 1996 · 1.3K citations

, , +12

Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling

Masahiro Yamamoto, Shintaro Sato, Kiyotoshi Mori et al. · The Journal of Immunology · 2002 · 1.2K citations · Full text

, , +17