Shuo Yang

Succination inactivates gasdermin D and blocks pyroptosis

Fiachra Humphries, Liraz Shmuel-Galia, Natália Ketelut-Carneiro et al. · Science · 2020 · 613 citations · Full text

Antiparasitic Agent, Apoptosis, Immunology +18

Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway

Jun Zeng, Yizhao Chen, Rui Ding et al. · Journal of Neuroinflammation · 2017 · 322 citations · Full text

Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis

Sheng Li, Yuqing Wu, Dongxue Yang et al. · The Journal of Experimental Medicine · 2019 · 205 citations · Full text

Gsdmd Deficiency, Gsdmd Protein, Immunology +19

The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome

Fiachra Humphries, Ronan Bergin, Ruaidhrí Jackson et al. · Nature Communications · 2018 · 197 citations · Full text

P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite

Liang Feng, Yizhao Chen, Rui Ding et al. · Journal of Neuroinflammation · 2015 · 174 citations · Full text