Concepedia

Interleukin-18 enhances Th1 immunity and tumor protection of a DNA vaccine

Deborah J. Marshall, Kelly A. Rudnick, Stephen G. McCarthy, Lani R. San Mateo, Michael Harris, Christine McCauley, Linda A. Snyder

Vaccine · 2005 · 68 citations · 24 references

DOI

Concepts

References

24

Cloning of a new cytokine that induces IFN-γ production by T cells

Haruki Okamura, Hiroko Tsutsui, Toshinori Komatsu et al. · Nature · 1995 · 2.6K citations

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IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12

Keizo Kohno, Jiro Kataoka, Takashi Ohtsuki et al. · The Journal of Immunology · 1997 · 520 citations

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Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization.

Eytan Raz, Helen Tighe, Yukio Sato et al. · Proceedings of the National Academy of Sciences · 1996 · 517 citations

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Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis.

Christina Coughlin, Kevin E. Salhany, Maria Wysocka et al. · Journal of Clinical Investigation · 1998 · 420 citations · Full text

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DNA vaccination: antigen presentation and the induction of immunity

Devon J. Shedlock, David B. Weiner · Journal of Leukocyte Biology · 2000 · 256 citations · Full text

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