Christina Coughlin

Phosphatidylinositol 3-Kinase α–Selective Inhibition With Alpelisib (BYL719) in <i>PIK3CA</i>-Altered Solid Tumors: Results From the First-in-Human Study

Dejan Juric, Jordi Rodón, Josep Tabernero et al. · Journal of Clinical Oncology · 2018 · 425 citations

Breast Oncology, Single-agent Alpelisib, Solid Tumors +17

Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis.

Christina Coughlin, Kevin E. Salhany, Maria Wysocka et al. · Journal of Clinical Investigation · 1998 · 420 citations · Full text

Angiogenesis Inhibition, Immunology, Immunoediting +18

Tumor Cell Responses to IFNγ Affect Tumorigenicity and Response to IL-12 Therapy and Antiangiogenesis

Christina Coughlin, Kevin E. Salhany, Michael S. Gee et al. · Immunity · 1998 · 319 citations · Full text

RNA-transfected CD40-activated B cells induce functional T-cell responses against viral and tumor antigen targets: implications for pediatric immunotherapy

Christina Coughlin, Barbara A. Vance, Stephan A. Grupp et al. · Blood · 2003 · 138 citations · Full text

B7-1 and interleukin 12 synergistically induce effective antitumor immunity.

Christina Coughlin, Maria Wysocka, H Kurzawa et al. · PubMed · 1995 · 118 citations

Immunology, Immunologic Mechanism, Immune System +19