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NR1I2 Polymorphisms Are Related to Tacrolimus Dose-Adjusted Exposure and BK Viremia in Adult Kidney Transplantation

DOI

46

Citations

18

References

2012

Year

Katherine A. Barraclough, Nicole M. Isbel, Katie J. Lee, Troels K. Bergmann, David W. Johnson, Brett McWhinney, Jacobus Ungerer, Scott B. Campbell, D. Leary, Seweryn Bialasiewicz,
Transplantation

Abstract

These data demonstrate an impact of pregnane X receptor polymorphisms on tacrolimus pharmacokinetics. Association of the 8055T allele with BK viremia suggests clinically significant "overimmunosuppression" in individuals with this genotype.

References

YearCitations

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