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Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity

Rodrigo Leite de Oliveira, Sofie Deschoemaeker, Anne‐Theres Henze, Koen Debackere, Veronica Finisguerra, Yukiji Takeda, Carmen Roncal, Daniela Dettori, Evelyne Tack, Yannick Jönsson,

Cancer Cell · 2012 · 124 citations · 45 references

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45

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Andrew Epstein, Jonathan Gleadle, Luke A. McNeill et al. · Cell · 2001 · 3.3K citations · Full text

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Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

Paolo P. Provenzano, Carlos Cuevas, Amy Chang et al. · Cancer Cell · 2012 · 2.1K citations · Full text

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Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation

Frank Winkler, Sergey V. Kozin, Ricky T. Tong et al. · Cancer Cell · 2004 · 1.2K citations · Full text

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Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

Massimiliano Mazzone, Daniela Dettori, Rodrigo Leite de Oliveira et al. · Cell · 2009 · 812 citations · Full text

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Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels

Christian Fischer, Bart Jonckx, Massimiliano Mazzone et al. · Cell · 2007 · 788 citations · Full text

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