Koen Debackere

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming

Haiping Wang, Xiaoyun Li, Tung Chao et al. · Nature Immunology · 2017 · 1.1K citations · Full text

Epigenetic Reprogramming, Metabolic Regulation, Metabolism +2

Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

Massimiliano Mazzone, Daniela Dettori, Rodrigo Leite de Oliveira et al. · Cell · 2009 · 802 citations · Full text

Oncology, Angiogenesis, Medicine +10

Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity

Rodrigo Leite de Oliveira, Sofie Deschoemaeker, Anne‐Theres Henze et al. · Cancer Cell · 2012 · 124 citations · Full text

Tumor Biology, Medicine, Cancer Biology +8

In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy

Lukas Marcelis, Asier Antoranz, Anne-Marie Delsupehe et al. · Cancer Immunology Immunotherapy · 2020 · 59 citations · Full text

Neuro-oncology, Immune Evasion, Tumor Immunology +12

Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified

Koen Debackere, Lukas Marcelis, Sofie Demeyer et al. · Nature Communications · 2021 · 34 citations · Full text