Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

Andrea Casazza, Damya Laoui, Mathias Wenes, +7

Cancer Cell

Restores Antitumor ImmunityCancer ResearchMacrophage EntryCancer ImmunosurveillanceAngiogenesis +11

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

Yukiji Takeda, Sandra Costa, Estelle Delamarre, +21

Nature

InflammationThrombosisVascular DiseaseAngiogenesisImmunology +13

Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity

Rodrigo Leite de Oliveira, Sofie Deschoemaeker, Anne‐Theres Henze, +16

Cancer Cell

Tumor BiologyMedicineCancer BiologyPrevents Side-toxicityAnti-cancer Agent +6

The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia

Giusy Di Conza, Sarah Trusso Cafarello, Stefan Loroch, +11

Cell Reports

Cell DeathCancer BiologyRedox BiologyTumor BiologyOxidative Stress +17

Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces systemic anti-tumor immunity

Ahmed E.I. Hamouda, Jessica Filtjens, Elisabeth Brabants, +26

Nature Communications

<scp>PHD</scp> 1 regulates p53‐mediated colorectal cancer chemoresistance

Sofie Deschoemaeker, Giusy Di Conza, Sérgio Lilla, +13

EMBO Molecular Medicine

Genetic Deficiency in Plasma Protein HRG Enhances Tumor Growth and Metastasis by Exacerbating Immune Escape and Vessel Abnormalization

Sònia Tugues, Satoshi Honjo, Christian König, +9

Cancer Research

ImmunologyImmunoeditingPathologyImmunotherapyCancer Biology +17

Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages

Aleksandar Murgaski, Máté Kiss, Helena Van Damme, +20

Cancer Research

ImmunologyImmunoeditingαCd40 Therapy ResponseCd4 T Cell ResponsesImmunotherapeutics +27

In Vivo Identification of Adducts from the New Hypoxia-Activated Prodrug CP-506 Using DNA Adductomics

Morwena J. Solivio, Alessia Stornetta, Julie Gilissen, +5

Chemical Research in Toxicology

Impact of <i>myo</i>‐inositol trispyrophosphate (ITPP) on tumour oxygenation and response to irradiation in rodent tumour models

Ly‐Binh‐An Tran, Thanh Trang Cao Pham, Bénédicte F. Jordan, +3

Journal of Cellular and Molecular Medicine