Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

Andrea Casazza, Damya Laoui, Mathias Wenes, +7

Cancer Cell

Restores Antitumor ImmunityCancer ResearchMacrophage EntryCancer ImmunosurveillanceAngiogenesis +11

MET is required for the recruitment of anti-tumoural neutrophils

Veronica Finisguerra, Giusy Di Conza, Mario Di Matteo, +9

Nature

GranulocyteMedicineImmunologyAnti-tumoural NeutrophilsOncology +3

miR-511-3p Modulates Genetic Programs of Tumor-Associated Macrophages

Mario Leonardo Squadrito, Ferdinando Pucci, Laura Magri, +8

Cell Reports

Sema3E–Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice

Andrea Casazza, Veronica Finisguerra, Lorena Capparuccia, +14

Journal of Clinical Investigation

AngiogenesisSema3e–plexin D1Tumor GrowthMedicineCancer Cell Biology +12

Plexin signaling hampers integrin‐based adhesion, leading to Rho‐kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility

Davide Barberis, Stefania Artigiani, Andrea Casazza, +6

The FASEB Journal

Hampers Integrin‐based AdhesionCell AdhesionPlexin ActivationMolecular BiologyLamellipodia Extension +14

Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity

Juan R. Hernández‐Fernaud, Elena Ruengeler, Andrea Casazza, +26

Nature Communications

Tumor BiologyOncologyCaf SecretomeOncogenic AgentMedicine +13

Systemic and Targeted Delivery of Semaphorin 3A Inhibits Tumor Angiogenesis and Progression in Mouse Tumor Models

Andrea Casazza, Xi Fu, Irja Johansson, +11

Arteriosclerosis Thrombosis and Vascular Biology

The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment

Charlotte Rolny, Lorena Capparuccia, Andrea Casazza, +7

The Journal of Experimental Medicine

ImmunologyImmunotherapyCancer BiologyTumor BiologyIl-8 Secretion +19

p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling

Davide Barberis, Andrea Casazza, Raffaella Sordella, +5

Journal of Cell Science

Cell AdhesionPlexin ActivationMolecular BiologyIntegrin-based AdhesionCytoskeleton +18

Tumour growth inhibition and anti‐metastatic activity of a mutated furin‐resistant Semaphorin 3E isoform

Andrea Casazza, Boaz Kigel, Federica Maione, +6

EMBO Molecular Medicine

Tumour Growth InhibitionTumor BiologyOncologyOncogenic AgentMedicine +8